An area of greatest vulnerability – Recent advances in kidney injuryArticle Published on 2022-08-012022-11-16 Journal: Biomedical journal [Category] SARS, 변종, [키워드] Acute kidney injury an area Atherosclerosis can be used Cell cerebral cerebral palsy children chronic Chronic kidney disease COVID-19 diagnose disorder HIV include invasive journal kidney Kidney injury long non-coding RNA metabolomics Metastasis multiple sclerosis observation Other Patient provided recent SARS-CoV-2 variant shown surfactant surfactant. Therapeutic approach therapy Tuberculosis [DOI] 10.1016/j.bj.2022.07.006 PMC 바로가기
T-cell proliferation assay for the detection of SARS-CoV-2-specific T-cellsSARS-CoV-2-특이적 T-세포 검출을 위한 T-세포 증식 분석Article Published on 2022-07-012022-09-11 Journal: Clinica chimica acta; international journal of cli [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료법, 치료제, [키워드] an area Analysis antibody approved AUC B-cell B-cell response blood sample Blood samples carried cellular cellular immune responses clinical setting clinical settings complex Control control group controls ELISA assay False positive False positives Health care Health care worker health care workers humoral Humoral and cellular immune responses IgG immune immune responses Immunoglobulin Immunoglobulin G Infection less lymphocyte lymphocyte transformation Lymphocyte transformation test majority membrane N and M non-infected nucleocapsid peptide peptide pool peptide pools proliferation Protein representing resulting ROC analysis S protein S1 subunit SARS-CoV-2 SARS-CoV-2 spike protein Spike protein Stimulation T-cell T-cell Response T-cell response. T-cell responses the S protein the S1 subunit the SARS-CoV-2 thymidine Trigger vaccinated individual vaccination Vaccines were recorded [DOI] 10.1016/j.cca.2022.05.025 PMC 바로가기 [Article Type] Article
Absence of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies in stray cats길 잃은 고양이에서 SARS-CoV-2 RNA 및 항-SARS-CoV-2 항체의 부재Article Published on 2022-07-012022-09-11 Journal: Transboundary and emerging diseases [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] affected an area anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibodies Blood Blood samples can not cats circulation collected colonies colony Contact COVID-19 COVID-19 pandemic decrease demonstration ELISA kit ELISA kits epidemiological evaluate followed by hospital Infection Interdigital MOST nasal one health Oropharyngeal Perspective positive question raise ranged real time Rectal swabs Registered reported RT-PCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 transmission seronegative seropositive serum serum antibodies serum antibody stray cats. Swab swabs the SARS-CoV-2 Transmission urban areas Viral Viral variants Virus neutralization were assessed [DOI] 10.1111/tbed.14200 PMC 바로가기 [Article Type] Article
Development of a Mortality Prediction Model in Hospitalised SARS-CoV-2 Positive Patients Based on Routine Kidney Biomarkers일상적인 신장 바이오마커를 기반으로 입원한 SARS-CoV-2 양성 환자의 사망률 예측 모델 개발Article Published on 2022-06-302022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), MERS, SARS, 바이오마커, [키워드] Acute kidney injury acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age AKI an area analysed AUROC Biomarker Blood blood test blood tests characteristic Cohort coronavirus COVID-19 creatinine develop development Ethnicity focus foundation hospital hospitalised Humber in-hospital mortality increased mortality Inpatients kidney Kidney function kidney function test Kidney function tests Kidney injury Logistic regression logistic regression model main outcome measure Model Mortality National Health Service NHS outcome Patient patients without AKI PCR test positive positive RT-PCR prediction prediction model. predictor prevalent random Random forest receiver operating characteristic regions respiratory resulting retrospective cohort study routine RT-PCR test SARS-CoV-2 SARS-CoV-2 infected patients SARS-CoV-2 positive patient SARS-CoV-2 positive patients severe acute respiratory syndrome Coronavirus Sex sodium test dataset Trust United Kingdom urea [DOI] 10.3390/ijms23137260 PMC 바로가기 [Article Type] Article
Aspartate transferase-to-platelet ratio index-plus: A new simplified model for predicting the risk of mortality among patients with COVID-19Aspartate transferase-to-platelet ratio index-plus: COVID-19 환자의 사망 위험을 예측하기 위한 새로운 단순화 모델Multicenter Study Published on 2022-04-282022-09-11 Journal: World journal of gastroenterology [Category] 바이오마커, [키워드] Admission age all consecutive adult patients All-cause in-hospital mortality an area analyses analyzed aspartate Aspartate transferase Aspartate transferase-to-platelet ratio index association Biomarker category clinically conducted confounders coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 mortality COVID-19 patients develop died ferritin Hospital mortality Hospital stay In-hospital in-hospital mortality include inclusion criteria independent independent of intensive care intensive care unit liver Liver injury Logistic regression Logistic regression analyses lung male median age medical record medical records Mortality multicenter cohort study on admission Patient patient cohort patients with COVID-19 performance Platelet Platelets Predictive predictor predictors presenting regression analysis retrieved retrospective risk SARS-CoV-2 Serum ferritin serum ferritin. significantly Spectrum syndrome university [DOI] 10.3748/wjg.v28.i16.1671 PMC 바로가기 [Article Type] Multicenter Study
Identification of Natural SARS-CoV-2 Infection in Seroprevalence Studies Among Vaccinated Populations백신 접종 집단 사이의 혈청유병성 연구에서 자연적인 SARS-CoV-2 감염의 확인Article Published on 2022-04-012022-09-11 Journal: Mayo Clinic proceedings [Category] COVID19(2023년), MERS, SARS, 진단, 치료법, [키워드] 95% CI Accuracy age All participants an area antibody Antibody assays Antibody testing Area Blood can not capillary capillary blood Cohort composed conducted determine determined by elevated enrolled enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay female Health care Health care worker health care workers identification IgG IgG antibodies IgG antibody IgGs individual individuals Infection MOST natural natural infection nucleocapsid nucleocapsid protein participant Participants performed Population predicted Protein reactive reactivity reported SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 nucleocapsid separated Seroprevalence significantly specificity Spike protein Spike proteins statistically vaccinated individuals vaccination Vaccination Status was determined was tested were assessed [DOI] 10.1016/j.mayocp.2022.02.002 PMC 바로가기 [Article Type] Article
Antiviral metabolite 3′-deoxy-3′,4′-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19항바이러스 대사 산물 3'-deoxy-3',4'-didehydro-cytidine은 혈청에서 검출 가능하며 COVID-19를 포함한 급성 바이러스 감염 식별Article Published on 2022-03-112022-09-11 Journal: Med (New York, N.Y.) [Category] MERS, 바이오마커, 유전자 메커니즘, 진단, 치료기술, 치료제, [키워드] 95% CI acute infection acute viral infection Admission an area Antiviral AUC Bacterial Bacterial infection Bacterial infections Biomarker characteristic CMPK2 Cohort correlated COVID-19 Critical cytidine ddhC detectable Diagnosis diagnostic diagnostics emergency department enzyme Enzymes examined FIVE Gene Expression healthy controls High-resolution highlight identify implicated in viral in vivo independent inflammatory conditions interferon Liquid chromatography management marker mass spectrometry metabolite metabolome metabolomics NIHR pandemic Patient precursor Profiling receiver operating characteristic receiver operating characteristic curve responsible sera serum significantly small molecule Support transcripts validation cohort viperin Viral viral infection viral infections viral. [DOI] 10.1016/j.medj.2022.01.009 PMC 바로가기 [Article Type] Article
Krebs von den Lungen-6 as Disease Severity Marker for COVID-19 Patients: Analytical Verification and Quality Assessment of the Tosoh AIA-360 Compared to Lumipulse G600IIKrebs von den Lungen-6, COVID-19 환자의 질병 심각도 지표: Lumipulse G600II와 비교한 Tosoh AIA-360의 분석 검증 및 품질 평가Article Published on 2022-02-152022-09-10 Journal: International Journal of Environmental Research an [Category] COVID19(2023년), MERS, SARS, 바이오마커, 치료기술, [키워드] an area analysed Analysis analytical validation article assessment AUC AUROC best Biomarker chemiluminescence comparable Concentration concentrations COVID COVID-19 COVID-19 patient COVID-19 patients cut-off value demonstrated detectable disease severity effective enzyme enzyme immunoassay evaluated fluorescent Fujirebio Hospitalized identify immunoassay interstitial pneumonia IQR Krebs von den Lungen-6 limit marker material median age non-severe patient non-severe patients Patient Quality reagent receiver reported Research ROC serum severe COVID-19 patients Siena significantly higher unit verification was measured [DOI] 10.3390/ijerph19042176 PMC 바로가기 [Article Type] Article
Saliva-based detection of COVID-19 infection in a real-world setting using reagent-free Raman spectroscopy and machine learning시약이 없는 라만 분광법 및 기계 학습을 사용하여 실제 환경에서 타액 기반 COVID-19 감염 감지General Published on 2022-02-092022-09-10 Journal: Journal of Biomedical Optics [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] acquisition an area approach AUC biofluids Chain Reaction changes in confounding factors Coronavirus disease-19 COVID-19 COVID-19 infection decrease detect develop Diseases Donor droplet droplets female include individual Infection Infectious diseases information involved less male molecular Non-invasive other infectious diseases PCR test polymerase chain polymerase chain reaction Raman spectroscopy reagent reagents reverse transcription reverse transcription polymerase chain reaction RT-PCR Saliva Screening sensitivity Sex specificity supernatant Taking variant variants variants of concern virus with COVID-19 yielding [DOI] 10.1117/1.JBO.27.2.025002 PMC 바로가기 [Article Type] General
Serum calprotectin as a novel biomarker for severity of COVID-19 diseaseCOVID-19 질병의 중증도에 대한 새로운 바이오마커로서의 혈청 칼프로텍틴Article Published on 2022-02-012022-09-11 Journal: Irish Journal of Medical Science [Category] MERS, 바이오마커, [키워드] age an area Analysis Biomarker Biomarkers blood cell C-reactive protein calprotectin Care clinical parameter Clinical parameters Clinical severity cohort study coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease COVID-19 patients cross-sectional diagnosis of COVID-19 disease ferritin fibrinogen groups hospitalized patient hospitalized patients ICU ICU patient ICU Patients Inflammation intensive care intensive care unit Laboratory Logistic regression analysis non-ICU non-ICU patients Patient patients patients hospitalized patients with COVID-19 predict procalcitonin Prognosis Prognostic value reactant regression analysis reported required retrospective ROC Curve SARS-CoV-2 SARS-CoV-2. serum severity of COVID-19 significantly higher study population the patient two group two groups White blood cell [DOI] 10.1007/s11845-021-02565-8 PMC 바로가기 [Article Type] Article